Yeah, me too. That's why I am here asking. I am not going to have any hair left if I don't figure it out soon.

Did you try venting the tank above the tank and filler level?

Eliminate the losing the ignition, see if you can rig up a timing light so you know if the spark stops at the same time while driving.
When it stops, if you remove the float level bungs and give he car a shake, does fuel come out?
When the car stops, have you tried removing the air cleaner and watching to see if the accelerator pump squirts fuel in?
When it stops, does it sputter or stop?
is the ignition feed hooked up to the main feed circuit breaker? The ignition uses a resistor wire, is the ignition compatible?

yep, did not fix it either.

Borrow a spark checker that taps a plug wire, not losing spark

I have checked bowl levels, sometimes its low, but never empty

Only driving it with no air cleaner, can't see or do anything with shaker installed, still squirting fuel when it shuts down.

when it stops, it acts likes its out of fuel, but I had a fuel pressure gauge tapped into it while driving never lost pressure.

all factory wiring, factory resistor wire, factory coil, which I have changed, even unhooked the factory rev limiter to see if it was shutting the car down.

Has factory carb spacer about 3/8" thick, which should eliminate boiling the fuel in the carb

It has to be losing fuel or spark unless the exhaust is clogged? I've seen it on modern cars where the cats will close up. Muffler batting? If that's not it, I'd swap the carb. It may have an internal clog in the primary circuit. Also, you may see a spark, but is it strong enough to jump the gap and still on every cylinder? Have you checked the coils resistance?

Describe the motor problem a little better......a quick die off would probably be electrical related.......stumbling before die off would be fuel. If there is any backfire.....could get into things like weak valve springs.

I starting to think its the floats hanging up or needle and seat issue. Its a brand new Holley, and I have adjusted everything to where its properly adjusted and purrs like a kitten in the shop, but the last couple times I have drove it now, it shuts down right after I stand on it like it running out of fuel. Whats driving me nuts is not the consistent failure, its the inconsistent way it shuts down.

Just swapped the coil, no change.

Already been into the heads. Had a vibration at idle I could not get out of it and found two cylinders that the valve were being held off the seat just enough to cause dead cylinder. Went through the heads and double checked everything there. I'm pretty certain its a fuel issue, just one I have yet to find.

Pull a plug to see if it's wet or dry when it dies.