I have done this many of times. Make sure you use good line & fittings though. I have used bulkheads to exit the frame. Makes for a rela nice clean look. To this you will have to do some minor fabwork to make that happen cleanly - but in the end a much cleaner and safer way IMO. I have also done tranny lines and battery cables. Not a good idea though to run both fuel lines & battery cables together on the same side!!
Not experience talking. Brakelines are the only ones I will not do. The should be supported well.
Brent