I have the same setup on a 70 Nova (g-bar and DSE tubs), and were only able to get a 305/35/20 in there, on a 10" wheel. There is a lot of room to the inside, but with a 12" wheel, there wouldn't of been enough clearance for a driver without rubbing everywhere. We had test fitted a 295/45/18 and it cleared about the same.
I say if you can fit the 12" and a 335mm tire, go for it! Post pics, I would be interested to see how it fits.
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