Be different...I say do it. I will say that you should balance your tires though as I've seen a significant imbalance in just the wheels alone and running fast on the asphalt is a bit different that doing it in the dirt. Personally, I'd go buy a few bags of airsoft pellets (cheap alternative to Dyna Beads) and put a few ounces in each tire when mounting them on the wheels. Innovative Balancing has charts on their website showing the amount to use for different tire sizes/types:
http://www.innovativebalancing.com/. This is a dynamic balancing method that will compensate with wear so it won't matter if you ever spin a tire on the rim or if you need to dismount and remount the tire.
These are a staple in the long haul semi ranks as well as a large part of the 4x4 crowd who get to deal with large imbalances on new tires...pretty tough to balance out a 54" Interco Bogger with lead.
Tobin
KORE3