IRS/Diff/halfshaft angle

[240RR]

I thought I posted something similar on here a few days ago but?

Anyway I need a little advice so I can move forward with my chassis.

Using an Infinity Q45 diff and axles with 350Z suspension...does not matter at this point but also 350Z engine and 6 speed.

Setting ride height at 3.5" at bottom of chassis so we will be riding low. My quandry is setting up the diff height. My understanding is that I need to firstly maintain proper driveshaft angles and in order to do that I will have to drop the diff. I currently have it set in a fixture that maintains 3 degrees angle in the halfshafts UP to the diff which is about what OEM is. This setup has the driveshaft running uphill a good bit which I think is bad! Plus I think it is going to put the OEM mounting locations of the upper control arm perilously close to the halfshaft.
So if I drop the diff to get the driveshaft angles correct it has the halfshafts running downhill to the diff...I am guessing 4 degrees.
MAIN QUESTION IS....ARE THE HALFSHAFTS GOING TO BE HAPPY RUNNING DOWNHILL? I am assuming they don't care as long as I don't get them bound up in bump and rebound?