Best handgun for home protection?

[Sieg]

The best defense weapon for anyone is the one that has become a natural extention of your mind, arms, and hands

Well said Ty!

My muscle memory is geared to the geometry of the 1911. I can shoot another handguns accurately (self-defense accuracy) as long as the barrel-grip angle is close to the 1911.

Sight pictures aren't an option in most self-defense situations and those angles related to muscle memory when point shooting are critical IMO.

If I point shoot for center mass X on a silhouette with a Glock at 7 yds my typical double tap group is high in the neck area.

Those who carry - Commit yourself to practice that creates muscle memory with what ever weapon you choose. It doesn't have to be live fire drills. Laser attachments make it easy to practice draw and point.

Remember the draw from concealment may well determine if you win or lose the race. The draw should be practiced equally if not more!