We can set up for the Coyote motor with no issues at all. Both the subframe system and the crossmember are designed with the same suspension geometry however I recommend you do a close inspection of your front sub rails. The Mustangs are prone to rot in that area. Our subframe system replaces the OE subrails all together and ties into the OE torque box location simplifying installation and reinforcing the front even further. If your OE rails are in good shape and you are only planning on some track and autocross abuse with alot of street miles, the front crossmember will suit you perfectly.
Here is complete Fast Track subframe system.
Here is the crossmember only with optional strut tower panels.